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ea0048p1 | Poster Presentations | SFEEU2017

Weight loss and associated improvements in cardiometabolic risk factors with liraglutide 3.0 mg in the SCALE Obesity and Prediabetes randomised, double-blind, placebo-controlled 3-year trial

McGowan Barbara , Fujioka Ken , Greenway Frank , Krempf Michel , Le Roux Carel , Vettor Roberto , Lilleore Soren , Astrup Arne

Aims/objectives: Obesity and prediabetes are risk factors for developing T2D. 510% weight-loss can reduce risk of developing T2D by >50%. The 3-year part of this phase 3 trial investigated effects of liraglutide 3.0 mg, as adjunct to diet+exercise, in delaying onset of T2D over 3 years, body-weight and cardiometabolic risk factors in adults with obesity or overweight with comorbidities, and diagnosed with prediabetes at screening.Methods: Indiv...

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ea0063p992 | Diabetes, Obesity and Metabolism 3 | ECE2019

IN-FOCUS France: an epidemiological survey on severe hypertriglyceridaemiae assessing the comparative burden of illness of familial chylomicronaemia syndrome (FCS) and multifactorial chylomicronaemia syndrome (MCS)

Moulin Philippe , Bouquillon Benoit , Valero Rene , Krempf Michel , Rigalleau Vincent , Ziegler Olivier , Verges Bruno , Lecerf Jean-Michel , Verdier Edouard , Charriere Sybil , Bruckert Eric

Background: Familial chylomicronaemia syndrome (FCS) is a rare, inherited disorder characterised by impaired clearance of triglyceride (TG)-rich lipoproteins from plasma, leading to severe hypertriglyceridaemia (HTG), which have major effects on both physical and mental health, and a markedly increased risk of acute pancreatitis. A large overlap in the phenotype between FCS and multifactorial chylomicronaemia syndrome (MCS) contributes to the inconsistency in how patients are ...

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Endocrine Abstracts

Weight loss and associated improvements in cardiometabolic risk factors with liraglutide 3.0 mg in the SCALE Obesity and Prediabetes randomised, double-blind, placebo-controlled 3-year trial

IN-FOCUS France: an epidemiological survey on severe hypertriglyceridaemiae assessing the comparative burden of illness of familial chylomicronaemia syndrome (FCS) and multifactorial chylomicronaemia syndrome (MCS)

BiosciAbstracts